csl/RBPJK Antibody (4E12)

Novus Biologicals, part of Bio-Techne | Catalog # H00003516-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 4E12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CSL Antibodies »

Product Specifications

Immunogen

RBPJ (NP_976029, 3 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. WIKRKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYC

Specificity

recombining binding protein suppressor of hairless (Drosophila)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for csl/RBPJK Antibody (4E12)

Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01]

Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01]

Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01] - Analysis of RBPJ expression in transfected 293T cell line by RBPJ monoclonal antibody (M01), clone 4E12.Lane 1: RBPJ transfected lysate(54.3 KDa).Lane 2: Non-transfected lysate.
Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01]

Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01]

Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01] - RBPJ monoclonal antibody (M01), clone 4E12 Analysis of RBPJ expression in Jurkat.

Applications for csl/RBPJK Antibody (4E12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CSL

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Long Name

Recombining Binding Protein Supressor of Hairless [CBF1, CSL]

Alternate Names

CBF1, IGKJRB1, KBF2, RBP-JK, RBPJ, RBPSUH

Entrez Gene IDs

3516 (Human)

Gene Symbol

RBPJ

OMIM

147183 (Human)

UniProt

NP_976029 (Human)

Additional CSL Products

Product Documents for csl/RBPJK Antibody (4E12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for csl/RBPJK Antibody (4E12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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