csl/RBPJK Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00003516-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CSL Antibodies »

Product Specifications

Immunogen

RBPJ (NP_056958.3, 1 a.a. - 487 a.a.) full-length human protein. MAPVVTGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS

Specificity

RBPJ - recombination signal binding protein for immunoglobulin kappa J region,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for csl/RBPJK Antibody

Western Blot: csl/RBPJK Antibody [H00003516-D01P]

Western Blot: csl/RBPJK Antibody [H00003516-D01P]

Western Blot: csl/RBPJK Antibody [H00003516-D01P] - Analysis of RBPJ expression in mouse testis.
Western Blot: csl/RBPJK Antibody [H00003516-D01P]

Western Blot: csl/RBPJK Antibody [H00003516-D01P]

Western Blot: csl/RBPJK Antibody [H00003516-D01P] - Analysis of RBPJ expression in human placenta.
Western Blot: csl/RBPJK Antibody [H00003516-D01P]

Western Blot: csl/RBPJK Antibody [H00003516-D01P]

Western Blot: csl/RBPJK Antibody [H00003516-D01P] - Analysis of RBPJ expression in transfected 293T cell line by RBPJ polyclonal antibody.Lane 1: RBPJ transfected lysate(54.30 KDa).Lane 2: Non-transfected lysate.

Applications for csl/RBPJK Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CSL

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Long Name

Recombining Binding Protein Supressor of Hairless [CBF1, CSL]

Alternate Names

CBF1, IGKJRB1, KBF2, RBP-JK, RBPJ, RBPSUH

Entrez Gene IDs

3516 (Human)

Gene Symbol

RBPJ

UniProt

NP_056958.3 (Human)

Additional CSL Products

Product Documents for csl/RBPJK Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for csl/RBPJK Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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