CTDSP1 Antibody (OTI1B6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-03456

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1B6

Concentration

0.44 mg/ml

View all CTDSP1 Antibodies »

Product Summary for CTDSP1 Antibody (OTI1B6)

Immunogen

Full length human recombinant protein of human CTDSP1 (NP_067021) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CTDSP1 Antibody (OTI1B6)

Western Blot: CTDSP1 Antibody (OTI1B6) [NBP2-03456]

Western Blot: CTDSP1 Antibody (OTI1B6) [NBP2-03456]

Western Blot: CTDSP1 Antibody (OTI1B6) [NBP2-03456] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTDSP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTDSP1.
Immunohistochemistry-Paraffin: CTDSP1 Antibody (OTI1B6) [NBP2-03456]

Immunohistochemistry-Paraffin: CTDSP1 Antibody (OTI1B6) [NBP2-03456]

Immunohistochemistry-Paraffin: CTDSP1 Antibody (OTI1B6) [NBP2-03456] - Staining of paraffin-embedded Human prostate tissue using anti-CTDSP1 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: CTDSP1 Antibody (OTI1B6) [NBP2-03456]

Immunohistochemistry-Paraffin: CTDSP1 Antibody (OTI1B6) [NBP2-03456]

Immunohistochemistry-Paraffin: CTDSP1 Antibody (OTI1B6) [NBP2-03456] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CTDSP1 mouse monoclonal antibody.
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Applications for CTDSP1 Antibody (OTI1B6)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.44 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CTDSP1

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells

Alternate Names

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1, NIF3, NLI-IF, NLIIFEC 3.1.3.16, NLI-interacting factor 3, SCP1Nuclear LIM interactor-interacting factor 3, Small CTD phosphatase 1, Small C-terminal domain phosphatase 1

Entrez Gene IDs

58190 (Human)

Gene Symbol

CTDSP1

Additional CTDSP1 Products

Product Documents for CTDSP1 Antibody (OTI1B6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CTDSP1 Antibody (OTI1B6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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