Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rabbit (93%), Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CX3CR1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to amino acids in a extracellular loop of human CX3CR1. The immunogen is located within amino acids 160 - 210 of CX3CR1. Amino Acid Squence: CLGDYPEVLQEIWP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (86%).

Specificity

At least two isoforms of CX3CR1 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CX3CR1 Antibody - BSA Free

Western Blot: CX3CR1 AntibodyBSA Free [NBP1-76872]

Western Blot: CX3CR1 AntibodyBSA Free [NBP1-76872]

Western Blot: CX3CR1 Antibody [NBP1-76872] - Analysis of CX3CR1 in THP-1 cell lysate in the absence (lane A) or presence (lane B) of blocking peptide with anti-CX3CR1 (EL) using NBP1-76872 at 1:500 dilution.
CX3CR1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CX3CR1 Antibody - BSA Free [NBP1-76872] -

Immunocytochemistry/ Immunofluorescence: CX3CR1 Antibody - BSA Free [NBP1-76872] - Immunofluorescence of CX3CR1 in THP-1 cells with CX3CR1 antibody at 20 ug/mL.
CX3CR1 Antibody - BSA Free

Immunohistochemistry: CX3CR1 Antibody - BSA Free [NBP1-76872] -

Immunohistochemistry: CX3CR1 Antibody - BSA Free [NBP1-76872] - Immunohistochemistry of CX3CR1 in human spleen cells with CX3CR1 antibody at 10 ug/mL.

Applications for CX3CR1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

0.5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: CX3CR1

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.

Long Name

CX3C Chemokine Receptor 1

Alternate Names

CMKbRL1, V28

Gene Symbol

CX3CR1

UniProt

P49238 (Human)

Additional CX3CR1 Products

Product Documents for CX3CR1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CX3CR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.