Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.

Alternate Names

CRG-2, CRG2, IP-10

Gene Symbol

CXCL10

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Product Specific Notices for CXCL10/IP-10/CRG-2 Antibody (6D4) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CXCL10/IP-10/CRG-2 Antibody (6D4) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59749

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Flow Cytometry

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Background: CXCL10/IP-10/CRG-2