CXCR1/IL-8RA Antibody (8F1-1-4) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43339B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-43339AF350

Alexa Fluor 405

NBP1-43339AF405

Alexa Fluor 488

NBP1-43339AF488

Alexa Fluor 532

NBP1-43339AF532

Alexa Fluor 594

NBP1-43339AF594

Alexa Fluor 647

NBP1-43339AF647

Alexa Fluor 700

NBP1-43339AF700

Alexa Fluor 750

NBP1-43339AF750

Allophycocyanin

NBP1-43339APC

Allophycocyanin/Cy7

NBP1-43339APCCY7

CoraFluor 1

NBP1-43339CL1

DyLight 350

NBP1-43339UV

DyLight 405

NBP1-43339V

DyLight 488

NBP1-43339G

DyLight 550

NBP1-43339R

DyLight 594

NBP1-43339DL594

DyLight 650

NBP1-43339C

DyLight 680

NBP1-43339FR

DyLight 755

NBP1-43339IR

FITC

NBP1-43339F

HRP

NBP1-43339H

Janelia Fluor 525

NBP1-43339JF525

Janelia Fluor 549

NBP1-43339JF549

Janelia Fluor 585

NBP1-43339JF585

Janelia Fluor 635

NBP1-43339JF635

Janelia Fluor 646

NBP1-43339JF646

Janelia Fluor 669

NBP1-43339JF669

mFluor Violet 450 SE

NBP1-43339MFV450

mFluor Violet 500 SE

NBP1-43339MFV500

mFluor Violet 610 SE

NBP1-43339MFV610

PE

NBP1-43339PE

PE/Atto594

NBP1-43339PEATT594

PE/Cy5.5

NBP1-43339PECY55

PE/Cy7

NBP1-43339PECY7

PerCP

NBP1-43339PCP

Forumulation

Catalog #

BSA Free

NBP1-43339

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Hamster

Applications

Flow Cytometry, Fluorophore-linked immunosorbent assay, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 8F1-1-4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CXCR1/IL-8RA Antibodies »

Product Summary for CXCR1/IL-8RA Antibody (8F1-1-4) [Biotin]

Immunogen

The immunogen for this antibody was CD181.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for CXCR1/IL-8RA Antibody (8F1-1-4) [Biotin]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Fluorophore-linked immunosorbent assay

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCR1/IL-8RA

CXCR1, also known as IL-8 RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8 RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness.

Long Name

Interleukin 8 Receptor A

Alternate Names

CD181, IL-8 RA, IL8RA

Entrez Gene IDs

3577 (Human)

Gene Symbol

CXCR1

UniProt

P25024 (Human)

Additional CXCR1/IL-8RA Products

Product Documents for CXCR1/IL-8RA Antibody (8F1-1-4) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for CXCR1/IL-8RA Antibody (8F1-1-4) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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