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Key Product Details

Species Reactivity

Mouse

Applications

CyTOF-ready, Flow Cytometry

Label

Alexa Fluor 532

Antibody Source

Monoclonal Rat IgG2A Clone # 220803R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

CHO Chinese hamster ovary cell line transfected with mouse CXCR3
Met1-Leu367
Accession # AAC40163

Specificity

Detects mouse CXCR3 in direct ELISAs.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Scientific Data Images for CXCR3 Antibody (220803R) [Alexa Fluor® 532]

CXCR3 Antibody (220803R) [Alexa Fluor® 532]

CXCR3 Antibody (220803R) [Alexa Fluor® 532] [FAB1685RX] -

CXCR3 Antibody (220803R) [Alexa Fluor® 532] [FAB1685RX] - Vial of Alexa Fluor 532 conjugated antibody. Alexa Fluor 532 is optimally excited at 532 nm by the Yellow-Green laser (561 nm) and has an emission maximum of 554 nm.

Applications for CXCR3 Antibody (220803R) [Alexa Fluor® 532]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCR3

CXCR3, also known as GPR9, is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). In humans, two alternatively spliced CXCR3 isoforms, CXCR3 and CXCR3B, have been identified and have different chemokine binding affinities. Human CXCR3 is 368 amino acids (aa) in length with a predicted molecular weight of 41 kDa. CXCR3B contains an additional N-terminal sequence and is 415 aa in length with a predicted molecular weight of 46 kDa. Mouse and rat CXCR3 share 86% aa sequence identity with human CXCR3. CXCR3 is expressed on leukocytes and is upregulated following T cell activation. It binds multiple CXC chemokines and is known to mediate leukocyte trafficking. CXCR3 has been implicated in neuroinflammatory and autoimmune diseases.

Alternate Names

CD183, CXCR3, GPR9

Additional CXCR3 Products

Product Documents for CXCR3 Antibody (220803R) [Alexa Fluor® 532]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CXCR3 Antibody (220803R) [Alexa Fluor® 532]

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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