Key Product Details

Species Reactivity

Human

Applications

CyTOF-reported, Flow Cytometry

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Recombinant Monoclonal Mouse IgG2B Clone # 56811

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CXCR6 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human CXCR6
Met1-Leu342
Accession # O00574

Specificity

Stains human CXCR6 transfectants but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for CXCR6 Antibody (56811) [DyLight 488]

Application
Recommended Usage

CyTOF-reported

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCR6

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

Alternate Names

Bonzo, CD186, CXCR6, STRL33

Gene Symbol

CXCR6

Additional CXCR6 Products

Product Documents for CXCR6 Antibody (56811) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CXCR6 Antibody (56811) [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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