CYP2A13 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06099

Novus Biologicals, part of Bio-Techne
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NBP3-06099-100ul
NBP3-06099-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CYP2A13 Antibodies »

Product Summary for CYP2A13 Antibody

Immunogen

Produced in rabbits immunized with E. coli-derived Human CYP2A13 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for CYP2A13 Antibody

Immunohistochemistry-Paraffin: CYP2A13 Antibody [NBP3-06099]

Immunohistochemistry-Paraffin: CYP2A13 Antibody [NBP3-06099]

Immunohistochemistry-Paraffin: CYP2A13 Antibody [NBP3-06099] - Immunochemical staining of human CYP2A13 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

Applications for CYP2A13 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CYP2A13

The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is involved in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.

Alternate Names

CPAD, CYP2A, CYPIIA13, cytochrome P450 2A13, cytochrome P450, family 2, subfamily A, polypeptide 13, cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13, EC 1.14.14.1

Gene Symbol

CYP2A13

Additional CYP2A13 Products

Product Documents for CYP2A13 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CYP2A13 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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