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Cystatin E/M/CST6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33433

Novus Biologicals, part of Bio-Techne
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NBP2-33433
NBP2-33433-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQQEKLRCDFEVLVVPWQNSSQLLKH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cystatin E/M/CST6 Antibody

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433]

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433]

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433] - Staining of human skin shows high expression.
Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433]

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433]

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433] - Staining of liver cancer.
Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433]

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433]

Immunohistochemistry-Paraffin: Cystatin E/M/CST6 Antibody [NBP2-33433] - Staining of human skeletal muscle shows low expression as expected.

Applications for Cystatin E/M/CST6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cystatin E/M

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Alternate Names

CST6

Gene Symbol

CST6

UniProt

Additional Cystatin E/M Products

Product Documents for Cystatin E/M/CST6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cystatin E/M/CST6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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