Cysteinyl Leukotriene R1/CysLTR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85356

Novus Biologicals, part of Bio-Techne
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NBP1-85356
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cysteinyl Leukotriene R1/CysLTR1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RLSTFRKHSLSSVTYVPRKKASLPE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cysteinyl Leukotriene R1/CysLTR1 Antibody

Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]

Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]

Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356] - Staining of human spleen shows strong cytoplasmic/membranous positivity in cells in red pulp.
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356] - Staining of human lung shows strong cytoplasmic positivity in macrophages.
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Applications for Cysteinyl Leukotriene R1/CysLTR1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cysteinyl Leukotriene R1/CysLTR1

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.

Long Name

Cysteinyl Leukotriene Receptor 1

Alternate Names

CysLT1, CysLTR1, Cysteinyl LeukotrieneR1, HG55, HMTMF81, LTD4 Receptor

Gene Symbol

CYSLTR1

Additional Cysteinyl Leukotriene R1/CysLTR1 Products

Product Documents for Cysteinyl Leukotriene R1/CysLTR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cysteinyl Leukotriene R1/CysLTR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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