Cysteinyl Leukotriene R1/CysLTR1 Products
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
3 results for "Cysteinyl Leukotriene R1/CysLTR1" in Products
3 results for "Cysteinyl Leukotriene R1/CysLTR1" in Products
Cysteinyl Leukotriene R1/CysLTR1 Products
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
| Applications: | ELISA |
Potent CysLT1 (LTD4) inverse agonist. Also MRP1 inhibitor
| Alternate Names: | L-660711 |
| Chemical Name: | 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid |
| Purity: | ≥98% (HPLC) |
PDE inhibitor (non-selective)
| Alternate Names: | KC-404 |
| Chemical Name: | 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone |
| Purity: | ≥98% (HPLC) |
