Cytochrome P450 1A2 Antibody (3B8C1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11913

Novus Biologicals, part of Bio-Techne
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NBP3-11913-25ug
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Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 3B8C1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 1A2 Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat cytochrome p450 proteins and mouse myeloma Ag8563 cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Cytochrome P450 1A2 Antibody (3B8C1)

Western Blot: Cytochrome P450 1A2 Antibody (3B8C1) [NBP3-11913]

Western Blot: Cytochrome P450 1A2 Antibody (3B8C1) [NBP3-11913]

Western Blot: Cytochrome P450 1A2 Antibody (3B8C1) [NBP3-11913] - Left: Western blot using CYP1A2 antibody on recombinant (2) CYP1B1, (3) CYP1A1 and (4) CYP1A2 (0.5 pmol per lane). Right: Immunohistochemical staining of formalin-fixed, paraffin-embedded normal human liver tissue section.

Applications for Cytochrome P450 1A2 Antibody (3B8C1)

Application
Recommended Usage

Immunohistochemistry

1 - 5 ug/ml

Western Blot

1 - 2 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 1A2

In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.

Long Name

Cytochrome P450 1A2

Alternate Names

CYP1A2, CYPIA2, Cytochrome P(3)450, Cytochrome P450 4, Cytochrome P450-P3

Gene Symbol

CYP1A2

UniProt

P05177 (Human)

Additional Cytochrome P450 1A2 Products

Product Documents for Cytochrome P450 1A2 Antibody (3B8C1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytochrome P450 1A2 Antibody (3B8C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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