Cytochrome P450 1A2 Antibody (F16 P2 D8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11912

Novus Biologicals, part of Bio-Techne
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NBP3-11912-200ug
NBP3-11912-25ug
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # F16 P2 D8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 1A2 Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with Synthetic peptide conjugated to ovalbumin derived from the C-terminus of CYP2A6 and mouse myeloma Ag8563 cells. Antigen identical in CYP2A6, 2A7 and 2A13. (Uniprot: P05177)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Cytochrome P450 1A2 Antibody (F16 P2 D8)

Western Blot: Cytochrome P450 1A2 Antibody (F16 P2 D8) [NBP3-11912]

Western Blot: Cytochrome P450 1A2 Antibody (F16 P2 D8) [NBP3-11912]

Western Blot: Cytochrome P450 1A2 Antibody (F16 P2 D8) [NBP3-11912] - Left: Western blot using CYP2A6 antibody on recombinant cytochrome p450 at 1 ug/ml. Right: Staining using CYP2A6 antibody on normal human liver tissue at 1 ug/ml.

Applications for Cytochrome P450 1A2 Antibody (F16 P2 D8)

Application
Recommended Usage

Western Blot

1 - 2 ug/ml
Application Notes
ELISA titer to be determined by end-user..
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 1A2

In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.

Long Name

Cytochrome P450 1A2

Alternate Names

CYP1A2, CYPIA2, Cytochrome P(3)450, Cytochrome P450 4, Cytochrome P450-P3

Gene Symbol

CYP1A2

UniProt

P05177 (Human)

Additional Cytochrome P450 1A2 Products

Product Documents for Cytochrome P450 1A2 Antibody (F16 P2 D8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytochrome P450 1A2 Antibody (F16 P2 D8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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