Cytohesin-1 Antibody (1D6)

Novus Biologicals, part of Bio-Techne | Catalog # H00009267-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1D6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytohesin-1 Antibodies »

Product Specifications

Immunogen

PSCD1 (AAH50452, 1 a.a. ~ 398 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH

Reactivity Notes

Human. Other species not tested.

Specificity

PSCD1 - pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Cytohesin-1 Antibody (1D6)

Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (1D6) [H00009267-M01]

Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (1D6) [H00009267-M01]

Immunocytochemistry/Immunofluorescence: Cytohesin-1 Antibody (1D6) [H00009267-M01] - Analysis of monoclonal antibody to PSCD1 on HeLa cell . Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: Cytohesin-1 Antibody (1D6) [H00009267-M01]

Immunohistochemistry-Paraffin: Cytohesin-1 Antibody (1D6) [H00009267-M01]

Immunohistochemistry-Paraffin: Cytohesin-1 Antibody (1D6) [H00009267-M01] - Analysis of monoclonal antibody to PSCD1 on formalin-fixed paraffin-embedded human spleen. Antibody concentration 3 ug/ml.
Sandwich ELISA: Cytohesin-1 Antibody (1D6) [H00009267-M01] - Detection limit for recombinant GST tagged PSCD1 is approximately 1ng/ml as a capture antibody.

Applications for Cytohesin-1 Antibody (1D6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin), immunofluorescence, and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cytohesin-1

Pleckstrin homology, Sec7 and coiled/coil domains 1 (PSCD1) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. PSCD1 protein is 83% homologous to PSCD2.

Alternate Names

B2-1, CYTH1, Cytohesin1, PSCD1, SEC7

Entrez Gene IDs

9267 (Human)

Gene Symbol

CYTH1

OMIM

182115 (Human)

UniProt

AAH50452 (Human)

Additional Cytohesin-1 Products

Product Documents for Cytohesin-1 Antibody (1D6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytohesin-1 Antibody (1D6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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