Cytokeratin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98734

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cytokeratin 1 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human Cytokeratin 1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Cytokeratin 1 Antibody

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734]

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734]

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in rat skin with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734]

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734]

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in human hepatoma with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734]

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734]

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in human malignant melanoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
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Applications for Cytokeratin 1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:250-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cytokeratin 1

Belonging to the keratin family, Cytokeratin 1 plays an important role in cell binding. More specifically, this gene is expressed in the spinous and granular layers of the epidermis with keratin 10. Mutations in this gene have been associated with the variants of bullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected. This gene also regulates the activity of kinases such as PKC and SRC by binding to ITGB1 and the receptor of GNB2L1. Other biological processes include complement activation, lectin pathway, epidermis development, fibrinolysis, regulation of angiogenesis and response to oxidative stress.

Alternate Names

CK1, CK-1, cytokeratin 1, Cytokeratin-1, cytokeratin-1,67 kDa cytokeratin, EHK, EHK1, epidermolytic hyperkeratosis 1, EPPK, Hair alpha protein, K1, keratin 1, keratin, type II cytoskeletal 1, Keratin-1, KRT1A, KRTA, NEPPK, Type-II keratin Kb1

Gene Symbol

KRT1

Additional Cytokeratin 1 Products

Product Documents for Cytokeratin 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cytokeratin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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