DAB2IP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30081

Novus Biologicals, part of Bio-Techne
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NBP1-30081
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all DAB2IP Antibodies »

Product Specifications

Immunogen

Antigen maps to a region between residue 850 and 900 of human disabled homolog 2 interacting protein using the numbering given in entry CAQ10385.1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

132 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DAB2IP Antibody

Western Blot: DAB2IP Antibody [NBP1-30081]

Western Blot: DAB2IP Antibody [NBP1-30081]

Western Blot: DAB2IP Antibody [NBP1-30081] - Detection of Mouse DAB2IP by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, Renca, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-DAB2IP antibody NBP1-30081 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Western Blot: DAB2IP Antibody [NBP1-30081]

Western Blot: DAB2IP Antibody [NBP1-30081]

Western Blot: DAB2IP Antibody [NBP1-30081] - Whole cell lysate from HeLa cells. DAB2IP was also IPed by rabbit anti-DAB2IP antibody NBP1-30082. For blotting immunoprecipitated DAB2IP, the ReliaBLOT (Trademark) Reagents and Procedures were used.

Applications for DAB2IP Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DAB2IP

DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene.

Alternate Names

AIP1FLJ39072, ASK-interacting protein 1, DAB2 interacting protein, DAB2 interaction protein, DAB2-interacting protein, DIP1/2, disabled homolog 2-interacting protein, DOC-2/DAB2 interactive protein, KIAA1743AF9Q34ASK1-interacting protein 1, nGAP-like protein

Entrez Gene IDs

153090 (Human)

Gene Symbol

DAB2IP

UniProt

Q5VWQ8 (Human)

Additional DAB2IP Products

Product Documents for DAB2IP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DAB2IP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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