DC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13678

Novus Biologicals, part of Bio-Techne
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NBP2-13678
NBP2-13678-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DC8 Antibodies »

Product Summary for DC8 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: FVQKLGDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DC8 Antibody

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678]

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678]

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678] - Staining in human lymph node and pancreas tissues using anti-NSL1 antibody. Corresponding NSL1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678]

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678]

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678] - Staining of human tonsil shows moderate nuclear positivity in germinal center cells and strong nuclear staining in non-germinal center cells.
Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678]

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678]

Immunohistochemistry-Paraffin: DC8 Antibody [NBP2-13678] - Staining of human lymph node shows high expression.
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Applications for DC8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For Immunofluorescence, Fixation/Permeabilization: PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DC8

DC8 encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. It is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

C1orf48, chromosome 1 open reading frame 48, DC8, DKFZP566O1646, kinetochore-associated protein NSL1 homolog, MIS14, NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

Gene Symbol

NSL1

Additional DC8 Products

Product Documents for DC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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