DcR3/TNFRSF6B Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76909

Novus Biologicals, part of Bio-Techne
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NBP1-76909
NBP1-76909SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DcR3/TNFRSF6B Antibodies »

Product Summary for DcR3/TNFRSF6B Antibody - BSA Free

Immunogen

Antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DcR3 precursor. The immunogen is located within the first 50 amino acids of DcR3. Amino Acid Squence: AETPTYPWRDAETGER

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

33 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DcR3/TNFRSF6B Antibody - BSA Free

Western Blot: DcR3/TNFRSF6B AntibodyBSA Free [NBP1-76909]

Western Blot: DcR3/TNFRSF6B AntibodyBSA Free [NBP1-76909]

Western Blot: DcR3/TNFRSF6B Antibody [NBP1-76909] - Analysis of DcR3 in human heart (H), brain (B), and kidney (K) tissue lysates with anti-DcR3 (NT) using NBP1-76909 at 1:500 dilution.
Immunohistochemistry-Paraffin: DcR3/TNFRSF6B Antibody - BSA Free [NBP1-76909]

Immunohistochemistry-Paraffin: DcR3/TNFRSF6B Antibody - BSA Free [NBP1-76909]

Immunohistochemistry-Paraffin: DcR3/TNFRSF6B Antibody [NBP1-76909] - Human heart tissue with DcR3 antibody at 1 ug/ml.

Applications for DcR3/TNFRSF6B Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

1 ug/ml

Immunohistochemistry-Paraffin

1 ug/ml

Western Blot

0.5 ug/ml
Application Notes
An approximately 33 kDa band can be detected in Western Blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DcR3/TNFRSF6B

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Long Name

Decoy Receptor 3

Alternate Names

M68, TNFRSF6B, TR6

Entrez Gene IDs

8771 (Human)

Gene Symbol

TNFRSF6B

UniProt

O95407

Additional DcR3/TNFRSF6B Products

Product Documents for DcR3/TNFRSF6B Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DcR3/TNFRSF6B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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