DDR1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-39011

Novus Biologicals, part of Bio-Techne
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NB110-39011
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Key Product Details

Species Reactivity

Validated:

Human, Porcine, Bat, Bovine, Canine, Equine, Monkey, Primate

Predicted:

Chimpanzee (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all DDR1 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human DDR1.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%).

Localization

C-terminal region of human

Specificity

Human DDR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDR2 (69%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for DDR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: DDR1 Antibody - BSA Free [NB110-39011]

Immunohistochemistry-Paraffin: DDR1 Antibody - BSA Free [NB110-39011]

Immunohistochemistry-Paraffin: DDR1 Antibody - BSA Free [NB110-39011] - Analysis of anti-DDR1 antibody with human decidual cells concentration 25 ug/ml.

Applications for DDR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 - 25 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: DDR1

DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.

Long Name

Discoidin Domain Receptor 1

Alternate Names

CAK, CD167a, RTK6, TrkE

Entrez Gene IDs

780 (Human)

Gene Symbol

DDR1

UniProt

Q08345

Additional DDR1 Products

Product Documents for DDR1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DDR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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