Dectin-1/CLEC7A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45514

Novus Biologicals, part of Bio-Techne
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NBP1-45514-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Dectin-1/CLEC7A Antibodies »

Product Specifications

Immunogen

Synthetic peptide surrounding amino acid 161 of human Dectin-1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

27.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab286157)

Scientific Data Images for Dectin-1/CLEC7A Antibody

Western Blot: Dectin-1/CLEC7A Antibody [NBP1-45514]

Western Blot: Dectin-1/CLEC7A Antibody [NBP1-45514]

Western Blot: Dectin-1/CLEC7A Antibody [NBP1-45514] - Analysis of Dectin-1 expression in lysate from rat kidney (Lane 1), 3T3 cells (Lane 2) and Jurkat cells (Lane 3 & 4).

Applications for Dectin-1/CLEC7A Antibody

Application
Recommended Usage

Western Blot

0.5 - 4 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 2 reviews rated 4.5 using NBP1-45514 in the following applications:

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2), 30% glycerol, 0.5% BSA

Preservative

0.01% Thimerosal

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Dectin-1/CLEC7A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Alternate Names

CD369, CLEC7A, CLECSF12, Dectin1

Entrez Gene IDs

64581 (Human)

Gene Symbol

CLEC7A

UniProt

Q9BXN2 (Human)

Additional Dectin-1/CLEC7A Products

Product Documents for Dectin-1/CLEC7A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Dectin-1/CLEC7A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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