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Derlin-3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16152

Novus Biologicals, part of Bio-Techne
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NBP2-16152

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (92%), Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Derlin-3. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Derlin-3 Antibody

Western Blot: Derlin-3 Antibody [NBP2-16152]

Western Blot: Derlin-3 Antibody [NBP2-16152]

Western Blot: Derlin-3 Antibody [NBP2-16152] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with DERL3 antibody [N3C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for Derlin-3 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Derlin-3

The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Alternate Names

C22orf14, chromosome 22 open reading frame 14, Degradation in endoplasmic reticulum protein 3, Der1-like domain family, member 3, Der1-like protein 3, DER3, derlin 3, derlin-3, DERtrin 3, DERtrin-3, FLJ43842, IZP6, LLN2, MGC71803

Gene Symbol

DERL3

UniProt

Additional Derlin-3 Products

Product Documents for Derlin-3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Derlin-3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.