Desmoplakin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48836

Novus Biologicals, part of Bio-Techne
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NBP2-48836-25ul
NBP2-48836
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Canine

Cited:

Mouse, Canine

Predicted:

Mouse (92%), Rat (91%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Desmoplakin Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NHNKVIETNRENDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKDMLANFRGSEKYCYLQNEVF

Reactivity Notes

Use in Canine reported in scientific literature (PMID:34983311).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Desmoplakin Antibody

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836]

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836]

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining in human skin and skeletal muscle tissues using anti-DSP antibody. Corresponding DSP RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836]

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836]

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining of human skeletal muscle shows low expression as expected.
Desmoplakin Antibody

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] -

Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining of human skin shows moderate cytoplasmic positivity in squamous epithelial cells.
View 1 more images

Applications for Desmoplakin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Reported in scientific literature (PMID:34983311)

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Desmoplakin

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Alternate Names

DCWHKTA, DPI, DPII, DSP, KPPS2, PPKS2

Gene Symbol

DSP

Additional Desmoplakin Products

Product Documents for Desmoplakin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Desmoplakin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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