Dfna5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87689

Novus Biologicals, part of Bio-Techne
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NBP1-87689
NBP1-87689-25ul
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Dfna5 Antibodies »

Product Summary for Dfna5 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dfna5 Antibody

Western Blot: Dfna5 Antibody [NBP1-87689]

Western Blot: Dfna5 Antibody [NBP1-87689]

Western Blot: Dfna5 Antibody [NBP1-87689] - Analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2,. Remaining relative intensity is presented. Loading control: Anti-PPIB.
Immunocytochemistry/ Immunofluorescence: Dfna5 Antibody [NBP1-87689]

Immunocytochemistry/ Immunofluorescence: Dfna5 Antibody [NBP1-87689]

Immunocytochemistry/Immunofluorescence: Dfna5 Antibody [NBP1-87689] - Staining of human cell line A-431 shows localization to cytosol. Antibody staining is shown in green.

Applications for Dfna5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04 - 0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dfna5

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

deafness, autosomal dominant 5, DFNA5, deafness associated tumor suppressor, gasdermin-E, ICERE1, ICERE-1, Inversely correlated with estrogen receptor expression 1, nonsyndromic hearing impairment protein, non-syndromic hearing impairment protein 5

Gene Symbol

GSDME

Additional Dfna5 Products

Product Documents for Dfna5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Dfna5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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