DHCR7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-84783

Novus Biologicals, part of Bio-Techne
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NBP2-84783-0.1ml
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all DHCR7 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DHCR7. Peptide sequence: AAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAP The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for DHCR7 Antibody

Western Blot: DHCR7 Antibody [NBP2-84783]

Western Blot: DHCR7 Antibody [NBP2-84783]

Western Blot: DHCR7 Antibody [NBP2-84783] - Host: Rabbit. Target Name: DHCR7. Sample Tissue: Human NCI-H226 Whole Cell lysates. Antibody Dilution: 1ug/ml

Applications for DHCR7 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DHCR7

The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the penultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. This enzyme removes the C(7-8) double bond introduced by the sterol delta8-delta7 isomerases. In addition, its role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis such as AY9944 and BM15766 severely impair brain development (Moebius et al., 1998 [PubMed 9465114]).[supplied by OMIM]

Alternate Names

7-dehydrocholesterol reductase, 7-DHC reductase, D7SR, delta-7-dehydrocholesterol reductase, EC 1.3.1, EC 1.3.1.21, Putative sterol reductase SR-2, SLOS, Smith-Lemli-Opitz syndrome, Sterol Delta(7)-reductase, sterol delta-7-reductase

Gene Symbol

DHCR7

Additional DHCR7 Products

Product Documents for DHCR7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DHCR7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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