DNA-PKcs [p Ser2056] Antibody (4A4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26398

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4A4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DNA-PKcs Antibodies »

Product Summary for DNA-PKcs [p Ser2056] Antibody (4A4)

Immunogen

A synthesized peptide derived from Human DNA-PKcs [p Ser2056] [UniProt P78527]

Modification

p Ser 2056

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DNA-PKcs [p Ser2056] Antibody (4A4)

DNA-PKcs [p Ser2056] Antibody (4A4)

Immunocytochemistry/Immunofluorescence: DNA-PKcs [p Ser2056] Antibody (4A4) [NBP3-26398] -

Immunocytochemistry/Immunofluorescence: DNA-PKcs [p Ser2056] Antibody (4A4) [NBP3-26398] - Staining of Hela cells(treated with UV) with DNA-PKcs [p Ser2056] Antibody (4A4) at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L).

Applications for DNA-PKcs [p Ser2056] Antibody (4A4)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: DNA-PKcs

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.(supplied by OMIM)

Long Name

DNA-dependent Protein Kinase Catalytic Subunit

Alternate Names

DNAPK, DNAPKcs, DNPK1, HYRC1, p350, PRKDC, XRCC7

Gene Symbol

PRKDC

Additional DNA-PKcs Products

Product Documents for DNA-PKcs [p Ser2056] Antibody (4A4)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DNA-PKcs [p Ser2056] Antibody (4A4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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