DOCK4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-26648

Novus Biologicals, part of Bio-Techne
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NBP1-26648
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

IF/IHC, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all DOCK4 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1725 and 1775 of human dedicator of cytokinesis 4 using the numbering given in entry NP_055520.3 (GeneID 9732).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DOCK4 Antibody

Western Blot: DOCK4 Antibody [NBP1-26648]

Western Blot: DOCK4 Antibody [NBP1-26648]

Western Blot: DOCK4 Antibody [NBP1-26648] - Whole cell lysate from HeLa and 293T cells. DOCK4 was also immunoprecipitated by rabbit anti-DOCK4 antibody NBP1-26649.
Immunohistochemistry-Paraffin: DOCK4 Antibody [NBP1-26648]

Immunohistochemistry-Paraffin: DOCK4 Antibody [NBP1-26648]

Immunohistochemistry-Paraffin: DOCK4 Antibody [NBP1-26648] - Human ovarian carcinoma. Antibody used at a dilution of 1:200 (1ug/ml).

Applications for DOCK4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500

Immunoprecipitation

3-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DOCK4

DOCK4 (dedicator of cytokinesis 4) is a member of the CDM gene family and functions as a guanine nucleotide exchange factor (GEF) for the Rac small GTPase. It has been found to play a role in regulating the development of dendrites and rac-dependent cell migration. As a regulator of Rac, DOCK4 participates in wnt signaling by acting as a scaffold and influencing beta-catenin stability.

Alternate Names

dedicator of cytokinesis 4, dedicator of cytokinesis protein 4, KIAA0716FLJ34238, MGC134911, MGC134912

Entrez Gene IDs

9732 (Human)

Gene Symbol

DOCK4

UniProt

NP_055520.3 (Human)

Additional DOCK4 Products

Product Documents for DOCK4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DOCK4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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