DOK1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77064

Novus Biologicals, part of Bio-Techne
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NBP1-77064
NBP1-77064-0.025mg
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DOK1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DOK1. The immunogen is located within amino acids 410 - 460 of DOK1. Amino Acid Squence: PQGPAFPEPGTATGS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

62 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DOK1 Antibody - BSA Free

Western Blot: DOK1 AntibodyBSA Free [NBP1-77064]

Western Blot: DOK1 AntibodyBSA Free [NBP1-77064]

Western Blot: DOK1 Antibody [NBP1-77064] - Jurkat (Jur) and THP-1 (THP) cell lysates with DOK1 antibody at 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: DOK1 Antibody - BSA Free [NBP1-77064]

Immunocytochemistry/ Immunofluorescence: DOK1 Antibody - BSA Free [NBP1-77064]

Immunocytochemistry/Immunofluorescence: DOK1 Antibody [NBP1-77064] - Immunofluorescence of DOK1 in K562 cells with DOK1 antibody at 10 ug/ml.
Immunocytochemistry/ Immunofluorescence: DOK1 Antibody - BSA Free [NBP1-77064]

Immunocytochemistry/ Immunofluorescence: DOK1 Antibody - BSA Free [NBP1-77064]

Immunocytochemistry/Immunofluorescence: DOK1 Antibody [NBP1-77064] - K562 cells with DOK1 antibody at 2 ug/ml.

Applications for DOK1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Western Blot

1 ug/ml
Application Notes
A 62 kDa band should be detected in Western Blot.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DOK1

Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok.

Alternate Names

docking protein 1, docking protein 1 (downstream of tyrosine kinase 1), docking protein 1, 62kD (downstream of tyrosine kinase 1), docking protein 1, 62kDa (downstream of tyrosine kinase 1), Downstream of tyrosine kinase 1, MGC117395, MGC138860, p62(dok), p62dok, pp62

Gene Symbol

DOK1

UniProt

AAC51127 (Human)

Additional DOK1 Products

Product Documents for DOK1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DOK1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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