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Dopa Decarboxylase/DDC Antibody (005)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89566

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-89566-100ul
NBP2-89566-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 005

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Dopa Decarboxylase/DDC Antibody (005)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human Dopa Decarboxylase/DDC (Accession#: NP_000781.1; Met 1-Glu 480).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Dopa Decarboxylase/DDC Antibody (005)

Immunohistochemistry-Paraffin: Dopa Decarboxylase/DDC Antibody (005) [NBP2-89566]

Immunohistochemistry-Paraffin: Dopa Decarboxylase/DDC Antibody (005) [NBP2-89566]

Immunohistochemistry-Paraffin: Dopa Decarboxylase/DDC Antibody (005) [NBP2-89566] - Staining of human DDC in human brain with rabbit monoclonal antibody (1:200). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).

Applications for Dopa Decarboxylase/DDC Antibody (005)

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunohistochemistry

1:100-1:500

Immunohistochemistry-Paraffin

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dopa Decarboxylase/DDC

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Alternate Names

AADC, DDC

Gene Symbol

DDC

Additional Dopa Decarboxylase/DDC Products

Product Documents for Dopa Decarboxylase/DDC Antibody (005)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dopa Decarboxylase/DDC Antibody (005)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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