Dopamine D2R/DRD2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1403

Novus Biologicals, part of Bio-Techne
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NLS1403
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Chimpanzee (100%), Monkey (95%), Primate (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all Dopamine D2 R/DRD2 Antibodies »

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human Dopamine D2R/DRD2.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Gibbon (95%), Canine (89%), Bovine (89%), Equine (89%), Porcine (89%), Mouse (84%), Rat (84%), Bat (84%), Hamster (84%).

Localization

Plasma membrane

Specificity

Human DRD2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZNF57 (42%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Dopamine D2R/DRD2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Dopamine D2R/DRD2 Antibody - BSA Free [NLS1403]

Immunohistochemistry-Paraffin: Dopamine D2R/DRD2 Antibody - BSA Free [NLS1403]

Immunohistochemistry-Paraffin: Dopamine D2 R/DRD2 Antibody [NLS1403] - Analysis of anti-DRD2 antibody with human brain, neurons and glia at 3 ug/ml.

Applications for Dopamine D2R/DRD2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 - 10 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Dopamine D2 R/DRD2

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

Long Name

Dopamine D2 Receptor

Alternate Names

D2DR, D2R, Dopamine D2R, DRD2

Entrez Gene IDs

1813 (Human)

Gene Symbol

DRD2

UniProt

P14416

Additional Dopamine D2 R/DRD2 Products

Product Documents for Dopamine D2R/DRD2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dopamine D2R/DRD2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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