Doublecortin Antibody (3E1) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92684B

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP1-92684

Alexa Fluor 350

NBP1-92684AF350

Alexa Fluor 405

NBP1-92684AF405

Alexa Fluor 488

NBP1-92684AF488

Alexa Fluor 532

NBP1-92684AF532

Alexa Fluor 594

NBP1-92684AF594

Alexa Fluor 647

NBP1-92684AF647

Alexa Fluor 700

NBP1-92684AF700

Alexa Fluor 750

NBP1-92684AF750

CoraFluor 1

NBP1-92684CL1

DyLight 350

NBP1-92684UV

DyLight 405

NBP1-92684V

DyLight 488

NBP1-92684G

DyLight 550

NBP1-92684R

DyLight 594

NBP1-92684DL594

DyLight 650

NBP1-92684C

DyLight 680

NBP1-92684FR

DyLight 755

NBP1-92684IR

FITC

NBP1-92684F

HRP

NBP1-92684H

Janelia Fluor 525

NBP1-92684JF525

Janelia Fluor 549

NBP1-92684JF549

Janelia Fluor 646

NBP1-92684JF646

Janelia Fluor 669

NBP1-92684JF669

mFluor Violet 450 SE

NBP1-92684MFV450

mFluor Violet 500 SE

NBP1-92684MFV500

mFluor Violet 610 SE

NBP1-92684MFV610

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Porcine, Bovine, Equine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG_2A Clone # 3E1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Doublecortin/DCX Antibodies »

Product Specifications

Immunogen

Recombinant full length human Lis-A isoform of Doublecortin purified from E. coli. [UniProt# O43602]

Localization

Cytoplasm. Cell projection. Note: Localizes at neurite tips.

Marker

Immature Neuronal Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for Doublecortin Antibody (3E1) [Biotin]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Doublecortin/DCX

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

Long Name

Doublecortin

Alternate Names

DBCN, Doublecortex, Doublin, Lis-X, LISX

Gene Symbol

DCX

Additional Doublecortin/DCX Products

Product Documents for Doublecortin Antibody (3E1) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Doublecortin Antibody (3E1) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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