DPP6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13212

Novus Biologicals, part of Bio-Techne
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NBP3-13212
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DPP6 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse DPP6. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for DPP6 Antibody

Western Blot: DPP6 Antibody [NBP3-13212]

Western Blot: DPP6 Antibody [NBP3-13212]

Western Blot: DPP6 Antibody [NBP3-13212] - Various tissue extracts (50 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with DPP6 antibody (NBP3-13212) diluted at 1:1000.
Immunohistochemistry-Frozen: DPP6 Antibody [NBP3-13212]

Immunohistochemistry-Frozen: DPP6 Antibody [NBP3-13212]

Immunohistochemistry-Frozen: DPP6 Antibody [NBP3-13212] - DPP6 antibody detects DPP6 protein expression by immunohistochemical analysis. Sample: Frozen-sectioned adult mouse hippocampus. Green: DPP6 protein stained by DPP6 antibody (NBP3-13212) diluted at 1:250. Blue: Fluoroshield with DAPI.
Immunohistochemistry-Paraffin: DPP6 Antibody [NBP3-13212]

Immunohistochemistry-Paraffin: DPP6 Antibody [NBP3-13212]

Immunohistochemistry-Paraffin: DPP6 Antibody [NBP3-13212] - DPP6 antibody detects DPP6 protein at cell membrane in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. DPP6 antibody (NBP3-13212) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for DPP6 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DPP6

The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.

Long Name

Dipeptidyl-peptidase 6

Alternate Names

DPPX

Gene Symbol

DPP6

Additional DPP6 Products

Product Documents for DPP6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DPP6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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