Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DRAK1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. The immunogen is located within the first 50 amino acids of DRAK1. Amino Acid Squence: EKPGSGGSSPGATSG

Specificity

No cross responses to DRAK2, DAP or ZIP kinases.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DRAK1 Antibody - BSA Free

Western Blot: DRAK1 AntibodyBSA Free [NBP1-76896]

Western Blot: DRAK1 AntibodyBSA Free [NBP1-76896]

Western Blot: DRAK1 Antibody [NBP1-76896] - Analysis for DRAK1 using this antibody at 2 ug/ml dilution against 10 ug/lane of MOLT4 (lane 1), A431 (lane 2) and NIH-3T3 (lane 3) cell lysates.
Immunocytochemistry/ Immunofluorescence: DRAK1 Antibody - BSA Free [NBP1-76896]

Immunocytochemistry/ Immunofluorescence: DRAK1 Antibody - BSA Free [NBP1-76896]

Immunocytochemistry/Immunofluorescence: DRAK1 Antibody [NBP1-76896] - Immunocytochemistry staining of MOLT4 cells using DRAK1 antibody at 2 ug/mL.
DRAK1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: DRAK1 Antibody - BSA Free [NBP1-76896] -

Immunocytochemistry/ Immunofluorescence: DRAK1 Antibody - BSA Free [NBP1-76896] - Immunofluorescence of DRAK1 in Molt cells with DRAK1 antibody at 20 ug/mL.

Applications for DRAK1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Western Blot

1 ug/ml
Application Notes
An approximately 50 kDa band can be detected in Western Blot.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DRAK1

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Long Name

DAP Kinase-related Apoptosis-inducing Protein Kinase 1

Alternate Names

STK17A

Gene Symbol

STK17A

UniProt

Q9UEE5

Additional DRAK1 Products

Product Documents for DRAK1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DRAK1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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