Drosha Antibody (4R0B7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15804

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4R0B7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Drosha Antibodies »

Product Summary for Drosha Antibody (4R0B7)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DROSHA (Q9NRR4). MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRP

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Drosha Antibody (4R0B7)

Western Blot: Drosha Antibody (4R0B7) [NBP3-15804]

Western Blot: Drosha Antibody (4R0B7) [NBP3-15804]

Western Blot: Drosha Antibody (4R0B7) [NBP3-15804] - Western blot analysis of extracts of various cell lines, using Drosha antibody (NBP3-15804) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Immunocytochemistry/ Immunofluorescence: Drosha Antibody (4R0B7) [NBP3-15804]

Immunocytochemistry/ Immunofluorescence: Drosha Antibody (4R0B7) [NBP3-15804]

Immunocytochemistry/Immunofluorescence: Drosha Antibody (4R0B7) [NBP3-15804] - Immunofluorescence analysis of HeLa cells using Drosha antibody (NBP3-15804). Blue: DAPI for nuclear staining.

Applications for Drosha Antibody (4R0B7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Drosha

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM]

Alternate Names

drosha, double-stranded RNA-specific endoribonuclease, drosha, ribonuclease type III, EC 3.1.26.3, ETOHI2, nuclear RNase III Drosha, p241, Protein Drosha, putative protein p241 which interacts with transcription factor Sp1, putative ribonuclease III, RANSE3L, ribonuclease 3, Ribonuclease III, ribonuclease III, nuclear, RN3nuclear, RNase III

Gene Symbol

DROSHA

Additional Drosha Products

Product Documents for Drosha Antibody (4R0B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Drosha Antibody (4R0B7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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