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DUSP14 Antibody (4B5-E6)

Novus Biologicals, part of Bio-Techne | Catalog # H00011072-M02

Novus Biologicals, part of Bio-Techne
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H00011072-M02

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4B5-E6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

DUSP14 (AAH00370, 1 a.a. ~ 198 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI

Reactivity Notes

Human. Other species not tested.

Specificity

DUSP14 - dual specificity phosphatase 14

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for DUSP14 Antibody (4B5-E6)

Immunocytochemistry/ Immunofluorescence: DUSP14 Antibody (4B5-E6) [H00011072-M02]

Immunocytochemistry/ Immunofluorescence: DUSP14 Antibody (4B5-E6) [H00011072-M02]

Immunocytochemistry/Immunofluorescence: DUSP14 Antibody (4B5-E6) [H00011072-M02] - Analysis of monoclonal antibody to DUSP14 on HeLa cell . Antibody concentration 10 ug/ml.
ELISA: DUSP14 Antibody (4B5-E6) [H00011072-M02]

ELISA: DUSP14 Antibody (4B5-E6) [H00011072-M02]

ELISA: DUSP14 Antibody (4B5-E6) [H00011072-M02] - Detection limit for recombinant GST tagged DUSP14 is approximately 1ng/ml as a capture antibody.

Applications for DUSP14 Antibody (4B5-E6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DUSP14

In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80; MIM 112203) and B7-2 (CD86; MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2; MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4; MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM]

Alternate Names

dual specificity phosphatase 14, EC 3.1.3.16, EC 3.1.3.48, MAP kinase phosphatase 6, Mitogen-activated protein kinase phosphatase 6, MKP-1 like protein tyrosine phosphatase, MKP-1-like protein tyrosine phosphatase, MKP-6, MKP6MKP-Ldual specificity protein phosphatase 14

Entrez Gene IDs

11072 (Human)

Gene Symbol

DUSP14

OMIM

606618 (Human)

Additional DUSP14 Products

Product Documents for DUSP14 Antibody (4B5-E6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DUSP14 Antibody (4B5-E6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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