DYNC1LI1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14935

Novus Biologicals, part of Bio-Techne
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NBP2-14935
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DYNC1LI1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human DYNC1LI1. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (100%), Bovine (86%), Chicken (83%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DYNC1LI1 Antibody

Western Blot: DYNC1LI1 Antibody [NBP2-14935]

Western Blot: DYNC1LI1 Antibody [NBP2-14935]

Western Blot: DYNC1LI1 Antibody [NBP2-14935] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE; antibody diluted at 1:5000.
Immunocytochemistry/ Immunofluorescence: DYNC1LI1 Antibody [NBP2-14935]

Immunocytochemistry/ Immunofluorescence: DYNC1LI1 Antibody [NBP2-14935]

Immunocytochemistry/Immunofluorescence: DYNC1LI1 Antibody [NBP2-14935] - Analysis of methanol-fixed A431, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: DYNC1LI1 Antibody [NBP2-14935]

Immunohistochemistry-Paraffin: DYNC1LI1 Antibody [NBP2-14935]

Immunohistochemistry-Paraffin: DYNC1LI1 Antibody [NBP2-14935] - Rat intestine. DYNC1LI1 antibody diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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Applications for DYNC1LI1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Immunoprecipitation

1:100-1:500

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DYNC1LI1

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Alternate Names

cytoplasmic dynein 1 light intermediate chain 1, DNCLI1, dynein, cytoplasmic 1, light intermediate chain 1, LIC1

Gene Symbol

DYNC1LI1

UniProt

Q9Y6G9 (Human)

Additional DYNC1LI1 Products

Product Documents for DYNC1LI1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DYNC1LI1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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