E2F6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14936

Novus Biologicals, part of Bio-Techne
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NBP2-14936
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (92%), Chimpanzee (100%), Rhesus Macaque (98%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all E2F6 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human E2F6. The exact sequence is proprietary.

Reactivity Notes

Mouse (80%), Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for E2F6 Antibody

Western Blot: E2F6 Antibody [NBP2-14936]

Western Blot: E2F6 Antibody [NBP2-14936]

Western Blot: E2F6 Antibody [NBP2-14936] - Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE E2F6 antibody, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: E2F6 Antibody [NBP2-14936]

Immunocytochemistry/ Immunofluorescence: E2F6 Antibody [NBP2-14936]

Immunocytochemistry/Immunofluorescence: E2F6 Antibody [NBP2-14936] - Paraformaldehyde-fixed A549, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: E2F6 Antibody [NBP2-14936]

Immunohistochemistry-Paraffin: E2F6 Antibody [NBP2-14936]

Immunohistochemistry-Paraffin: E2F6 Antibody [NBP2-14936] - H441 xenograft, using E2F6 antibody at 1:500 dilution. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

Applications for E2F6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: E2F6

This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq]

Alternate Names

E2F transcription factor 6, E2F-6MGC111545, transcription factor E2F6

Gene Symbol

E2F6

UniProt

O75461 (Human)

Additional E2F6 Products

Product Documents for E2F6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for E2F6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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