ELKS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88179

Novus Biologicals, part of Bio-Techne
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NBP1-88179
NBP1-88179-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ELKS Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQLQDELEKGERDNAELQEFANAILQQIADHCPD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ELKS Antibody

Western Blot: ELKS Antibody [NBP1-88179]

Western Blot: ELKS Antibody [NBP1-88179]

Western Blot: ELKS Antibody [NBP1-88179] - Analysis using Anti-ERC1 antibody NBP1-88179 (A) shows similar pattern to independent antibody NBP1-88178 (B).
Immunocytochemistry/ Immunofluorescence: ELKS Antibody [NBP1-88179]

Immunocytochemistry/ Immunofluorescence: ELKS Antibody [NBP1-88179]

Immunocytochemistry/Immunofluorescence: ELKS Antibody [NBP1-88179] - Staining of human cell line U-251 MG shows positivity in plasma membrane & focal adhesion sites. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: ELKS Antibody [NBP1-88179]

Immunohistochemistry-Paraffin: ELKS Antibody [NBP1-88179]

Immunohistochemistry-Paraffin: ELKS Antibody [NBP1-88179] - Staining of human kidney shows strong membranous and cytoplasmic positivity in cells in tubules and glomeruli.
View 1 more images

Applications for ELKS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ELKS

Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. The protein is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Five transcript variants encoding different isoforms have been found for this gene.

Alternate Names

ELKS/RAB6-interacting/CAST family member 1, ELKSCAST2, ERC-1, FLJ31750, KIAA1081Cast2, MGC12974, RAB6 interacting protein 2, Rab6-interacting protein 2, RAB6IP2

Gene Symbol

ERC1

Additional ELKS Products

Product Documents for ELKS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ELKS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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