ERCC1 Antibody (ERCC1/2318) [DyLight 350]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08903UV

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-07161

Alexa Fluor 350

NBP3-08903AF350

Alexa Fluor 405

NBP3-08903AF405

Alexa Fluor 488

NBP3-08903AF488

Alexa Fluor 532

NBP3-08903AF532

Alexa Fluor 594

NBP3-08903AF594

Alexa Fluor 647

NBP3-08903AF647

Alexa Fluor 700

NBP3-08903AF700

Alexa Fluor 750

NBP3-08903AF750

Allophycocyanin

NBP3-08903APC

Biotin

NBP3-08903B

CoraFluor 1

NBP3-08903CL1

DyLight 405

NBP3-08903V

DyLight 488

NBP3-08903G

DyLight 550

NBP3-08903R

DyLight 594

NBP3-08903DL594

DyLight 650

NBP3-08903C

DyLight 680

NBP3-08903FR

DyLight 755

NBP3-08903IR

FITC

NBP3-08903F

HRP

NBP3-08903H

Janelia Fluor 525

NBP3-08903JF525

Janelia Fluor 549

NBP3-08903JF549

Janelia Fluor 646

NBP3-08903JF646

Janelia Fluor 669

NBP3-08903JF669

PE

NBP3-08903PE

PerCP

NBP3-08903PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-08903

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Protein Array, Western Blot

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # ERCC1/2318

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ERCC1 Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary) (Uniprot: P07992)

Localization

Nuclear

Marker

Tumor Progression Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for ERCC1 Antibody (ERCC1/2318) [DyLight 350]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ERCC1

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1 XPF complex makes the 5'incision. Elevated levels of ERCC1 have also been reported in Cisplatin resistant cells.

Long Name

Excision Repair Cross-complementing 1

Alternate Names

COFS4, DNA excision repair protein ERCC-1, excision repair cross-complementing rodent repair deficiency, complementationgroup 1 (includes overlapping antisense sequence), RAD10, UV20

Gene Symbol

ERCC1

Additional ERCC1 Products

Product Documents for ERCC1 Antibody (ERCC1/2318) [DyLight 350]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ERCC1 Antibody (ERCC1/2318) [DyLight 350]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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