ERCC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00001161-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ERCC8 Antibodies »

Product Specifications

Immunogen

ERCC8 (NP_000073.1, 1 a.a. - 396 a.a.) full-length human protein. MLGFLSARQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for ERCC8 Antibody

Western Blot: ERCC8 Antibody [H00001161-B01P]

Western Blot: ERCC8 Antibody [H00001161-B01P]

Western Blot: ERCC8 Antibody [H00001161-B01P] - Analysis of ERCC8 expression in NIH/3T3.
Immunocytochemistry/ Immunofluorescence: ERCC8 Antibody [H00001161-B01P]

Immunocytochemistry/ Immunofluorescence: ERCC8 Antibody [H00001161-B01P]

Immunocytochemistry/Immunofluorescence: ERCC8 Antibody [H00001161-B01P] - Analysis of purified antibody to ERCC8 on HeLa cell. (antibody concentration 10 ug/ml)
Western Blot: ERCC8 Antibody [H00001161-B01P]

Western Blot: ERCC8 Antibody [H00001161-B01P]

Western Blot: ERCC8 Antibody [H00001161-B01P] - Analysis of ERCC8 expression in transfected 293T cell line by ERCC8 polyclonal antibody. Lane 1: ERCC8 transfected lysate(43.56 KDa). Lane 2: Non-transfected lysate.

Applications for ERCC8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for WB, Functional and IF.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ERCC8

ERCC8 encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Alternate Names

CKN1DNA excision repair protein ERCC-8, Cockayne syndrome 1 (classical), Cockayne syndrome WD repeat protein CSA, CSACockayne syndrome WD-repeat protein CSA, excision repair cross-complementing rodent repair deficiency, complementationgroup 8

Gene Symbol

ERCC8

UniProt

NP_000073.1 (Human)

Additional ERCC8 Products

Product Documents for ERCC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ERCC8 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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