ERCC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32166

Novus Biologicals, part of Bio-Techne
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NBP1-32166
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Functional, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ERCC8 Antibodies »

Product Summary for ERCC8 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human ERCC8. The exact sequence is proprietary.

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ERCC8 Antibody

Western Blot: ERCC8 Antibody [NBP1-32166]

Western Blot: ERCC8 Antibody [NBP1-32166]

Western Blot: ERCC8 Antibody [NBP1-32166] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with ERCC8 antibody [N2C2], Internal diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: ERCC8 Antibody [NBP1-32166]

Immunocytochemistry/ Immunofluorescence: ERCC8 Antibody [NBP1-32166]

Immunocytochemistry/Immunofluorescence: ERCC8 Antibody [NBP1-32166] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.
Western Blot: ERCC8 Antibody [NBP1-32166]

Western Blot: ERCC8 Antibody [NBP1-32166]

Western Blot: ERCC8 Antibody [NBP1-32166] - A. Neuro2A whole cell lysate/extract. B. GL261 whole cell lysate/extract. C. C8D30 whole cell lysate/extract. D. NIH-3T3 whole cell lysate/extract. E. Raw264.7 whole cell lysate/extract. F. C2C12 whole cell lysate/extract.

Applications for ERCC8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Application Notes
Functional Assay- Assay dependent
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ERCC8

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Alternate Names

CKN1DNA excision repair protein ERCC-8, Cockayne syndrome 1 (classical), Cockayne syndrome WD repeat protein CSA, CSACockayne syndrome WD-repeat protein CSA, excision repair cross-complementing rodent repair deficiency, complementationgroup 8

Gene Symbol

ERCC8

Additional ERCC8 Products

Product Documents for ERCC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ERCC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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