ERK3/MAPK6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99003

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ERK3 Antibodies »

Product Summary for ERK3/MAPK6 Antibody

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human ERK3/MAPK6.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ERK3/MAPK6 Antibody

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003]

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003]

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003] - Immunochemical staining of human ERK3/MAPK6 in rat heart with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003]

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003]

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003] - Immunochemical staining of human ERK3/MAPK6 in cynomolgus heart with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003]

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003]

Immunohistochemistry-Paraffin: ERK3/MAPK6 Antibody [NBP2-99003] - Immunochemical staining of human ERK3/MAPK6 in mouse heart with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

Applications for ERK3/MAPK6 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ERK3

ERK3 (Extracellular signal-regulated kinase 3, MAPK6, p97 MAPK) belongs to the Ser/Thr protein kinase family and is a member of the mitogen-activated protein (MAP) kinase superfamily. Unlike the other members of the MAPK family, ERK3 is a mitogen-activated protein kinase homologue that has SEG motif instead of conserved TXY motif in the activation loop (1). Also, unlike ERK1 and ERK2, it is ubiquitously expressed and localized in the nucleus of proliferating cells (2). Highly unstable, ERK3 is constitutively degraded during ubiquitin-proteasome pathway of proliferating cells (3). ERK3 has been linked to phosphorylation MAP2 and as a possible regulator during cell differentiation (4).

Long Name

Extracellular Signal-regulated Kinase 3

Alternate Names

MAPK6, p97MAPK

Gene Symbol

MAPK6

Additional ERK3 Products

Product Documents for ERK3/MAPK6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ERK3/MAPK6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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