ERp72 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB120-11422

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ERp72 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of humna ERp72.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse and Rat (88%).

Localization

Endoplasmic reticulum

Specificity

This detects ERp72 protein in human samples.

Marker

Endoplasmic Reticulum Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ERp72 Antibody - BSA Free

Western Blot: ERp72 AntibodyBSA Free [NB120-11422]

Western Blot: ERp72 AntibodyBSA Free [NB120-11422]

Western Blot: ERp72 Antibody [NB120-11422] - HT 1080 cell lysate.

Applications for ERp72 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:500

Western Blot

1:100 - 1:1000
Application Notes
WB: Detects an approx. 72 kDa protein representing ERp72 in human fibrosarcoma HT 1080 cell lysate.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.01% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ERp72

ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone.

Alternate Names

Endoplasmic reticulum resident protein 70, Endoplasmic reticulum resident protein 72, ER protein 70, ERp70, ERP70ER protein 72, ERp72, ERp-72, ERP72EC 5.3.4.1, intestinal-related), protein disulfide isomerase family A, member 4, protein disulfide isomerase related protein (calcium-binding protein, protein disulfide isomerase-associated 4, protein disulfide-isomerase A4

Entrez Gene IDs

9601 (Human)

Gene Symbol

PDIA4

Additional ERp72 Products

Product Documents for ERp72 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ERp72 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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