ESX1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77114

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ESX1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide near the center of human ESX1. The immunogen is located within amino acids 140 - 190 of ESX1. Amino Acid Squence: QFQLQELENFFDESQYPDV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ESX1 Antibody - BSA Free

Western Blot: ESX1 AntibodyBSA Free [NBP1-77114]

Western Blot: ESX1 AntibodyBSA Free [NBP1-77114]

Western Blot: ESX1 Antibody [NBP1-77114] - Human testis tissue lysate with ESX1 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: ESX1 Antibody - BSA Free [NBP1-77114]

Immunocytochemistry/ Immunofluorescence: ESX1 Antibody - BSA Free [NBP1-77114]

Immunocytochemistry/Immunofluorescence: ESX1 Antibody [NBP1-77114] - Immunofluorescence of ESX1 in human testis tissue with ESX1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: ESX1 Antibody - BSA Free [NBP1-77114]

Immunohistochemistry-Paraffin: ESX1 Antibody - BSA Free [NBP1-77114]

Immunohistochemistry-Paraffin: ESX1 Antibody [NBP1-77114] - Human testis tissue with ESX1 antibody at 2.5 ug/mL.
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Applications for ESX1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ESX1

Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.

Alternate Names

ESX homeobox 1, ESX1LESX1R, ESX1-related protein, ESXR1homeobox protein ESX1, Extraembryonic, spermatogenesis, homeobox 1, extraembryonic, spermatogenesis, homeobox 1 homolog, extraembryonic, spermatogenesis, homeobox 1 homolog (mouse)

Gene Symbol

ESX1

UniProt

Q8N693 (Human)

Additional ESX1 Products

Product Documents for ESX1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ESX1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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