ETV3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80931

Novus Biologicals, part of Bio-Techne
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NBP1-80931
NBP1-80931-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ETV3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EKEEHTQEEGTVPSRTIEEEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRWNDDPEARELSKSGKFLWNG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ETV3 Antibody

Western Blot: ETV3 Antibody [NBP1-80931]

Western Blot: ETV3 Antibody [NBP1-80931]

Western Blot: ETV3 Antibody [NBP1-80931] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17. Lane 2: Human cell line RT-4
Immunocytochemistry/ Immunofluorescence: ETV3 Antibody [NBP1-80931]

Immunocytochemistry/ Immunofluorescence: ETV3 Antibody [NBP1-80931]

Immunocytochemistry/Immunofluorescence: ETV3 Antibody [NBP1-80931] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: ETV3 Antibody [NBP1-80931]

Immunohistochemistry-Paraffin: ETV3 Antibody [NBP1-80931]

Immunohistochemistry-Paraffin: ETV3 Antibody [NBP1-80931] - Staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.

Applications for ETV3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ETV3

The ETV3 gene encodes an ETS translocation variant 3 protein, that in isoform 1 is 512 amino acids long at 57 kDA and in isoform 2 is 143 amino acids long at nearly 17 kDA. This protein functions in terminal macrophage differentiation as a transcriptional repressor that contributes to growth arrest. It also represses MMP1 promoter activity and interacts with the MYC and DDX20 genes. ETV3 is linked to diseases heart disease, hypertension, ADHD, and conduct disorder.

Alternate Names

bA110J1.4, ETS domain transcriptional repressor PE1, ETS translocation variant 3, ets variant 3, ets variant gene 3, ETS family transcriptional repressor, METS, Mitogenic Ets transcriptional suppressor, PE-1ets variant gene 3, PE1FLJ79173

Entrez Gene IDs

2117 (Human)

Gene Symbol

ETV3

Additional ETV3 Products

Product Documents for ETV3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ETV3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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