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EWSR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-75256

Novus Biologicals, part of Bio-Techne
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NB100-75256
NB100-75256-0.025mg

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for EWSR1 Antibody

Immunogen

The immunogen for this antibody was a sequence from 380a.a. to 448a.a. from RNA-binding protein EWSR1(a 656a.a. long protein)

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Localization

Cell surface, Cytoplasmic and Nuclear. Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation.

Specificity

RNA-binding protein EWSR1

Clonality

Polyclonal

Host

Chicken

Scientific Data Images for EWSR1 Antibody

Western Blot: EWSR1 Antibody [NB100-75256]

Western Blot: EWSR1 Antibody [NB100-75256]

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-EWSR1)

Applications for EWSR1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Anti-EWSR1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EWSR1

Might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking. or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Long Name

RNA-binding protein EWS

Alternate Names

EWS, EWS oncogene

Entrez Gene IDs

2130 (Human); 14030 (Mouse); 289752 (Rat)

Gene Symbol

EWSR1

UniProt

Additional EWSR1 Products

Product Documents for EWSR1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for EWSR1 Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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