FACA/FANCA Antibody (SR1233)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22105
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # SR1233
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
A synthesized peptide derived from human FACA/FANCA (Uniprot #: O15360)
Specificity
Detects endogenous levels of total FACA/FANCA
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
163 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for FACA/FANCA Antibody (SR1233)
Western Blot: FACA/FANCA Antibody (SR1233) [NBP3-22105] -
Western Blot: FACA/FANCA Antibody (SR1233) [NBP3-22105] - Western blot analysis using NBP3-22105 in A431 cell lysate.Applications for FACA/FANCA Antibody (SR1233)
Application
Recommended Usage
Immunoprecipitation
1:40
Western Blot
1:500-1:1000
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: FACA/FANCA
Defects in FANCA result in Fanconi Anemia, a genetically heterogeneous autosomal recessive disorder characterized by progressive pancytopenia, diverse congenital malformations, and a predisposition to develop malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. At the cellular level FANCA defects cause a hypersensitivity to DNA-damaging agents, chromosomal instability, and defective DNA repair.
Long Name
Fanconi Anemia, Complementation Group A
Alternate Names
FAA, FAH, FANCA, FANCH
Gene Symbol
FANCA
Additional FACA/FANCA Products
Product Documents for FACA/FANCA Antibody (SR1233)
Product Specific Notices for FACA/FANCA Antibody (SR1233)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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