Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all FAM120A Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid synthetic peptide from near the center of human FAM120A. The immunogen is located within amino acids 610 - 660 of FAM120A. Amino Acid Squence: SRKKTERLAFRKNRLPPE

Specificity

This antibody will not cross-react with FAM120B / PGCC1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FAM120A Antibody - BSA Free

Western Blot: FAM120A AntibodyBSA Free [NBP1-77367]

Western Blot: FAM120A AntibodyBSA Free [NBP1-77367]

Western Blot: FAM120A Antibody [NBP1-77367] - SK-N-SH cell lysate with FAM120A antibody at (A) 0.5 and (B) 1 ug/ml.
FAM120A Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: FAM120A Antibody - BSA Free [NBP1-77367] -

Immunocytochemistry/ Immunofluorescence: FAM120A Antibody - BSA Free [NBP1-77367] - Immunofluorescence of FAM120A in Rat Brain cells with FAM120A antibody at 20 u/mL.
FAM120A Antibody - BSA Free

Immunohistochemistry: FAM120A Antibody - BSA Free [NBP1-77367] -

Immunohistochemistry: FAM120A Antibody - BSA Free [NBP1-77367] - Immunohistochemistry of FAM120A in rat brain tissue with FAM120A antibody at 2.5 ug/mL.

Applications for FAM120A Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FAM120A

FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells. This antibody will not cross-reacti with FAM120B / PGCC1.

Alternate Names

C9orf10MGC133257, chromosome 9 open reading frame 10, constitutive coactivator of PPAR-gamma-like protein 1, DNA polymerase-transactivated protein 1, DNA polymerase-transactivated protein 5, DNAPTP1, DNAPTP5, family with sequence similarity 120A, KIAA0183MGC111527, OSSA, Oxidative stress-associated Src activator, Protein FAM120A

Gene Symbol

FAM120A

UniProt

NP_055427 (Human)

Additional FAM120A Products

Product Documents for FAM120A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FAM120A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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