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FANCC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12777

Novus Biologicals, part of Bio-Techne
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NBP3-12777-100ul
NBP3-12777-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for FANCC Antibody

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human FANCC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Scientific Data Images for FANCC Antibody

Immunocytochemistry/ Immunofluorescence: FANCC Antibody [NBP3-12777]

Immunocytochemistry/ Immunofluorescence: FANCC Antibody [NBP3-12777]

Immunocytochemistry/Immunofluorescence: FANCC Antibody [NBP3-12777] - Staining of FANCC in HeLa cells. Cells were fixed with 4% PFA,blocked with 10% serum. Then incubated with rabbit anti-human FANCC polyclonal antibody (1:1000)(Figure A), incubated with rabbit anti-human FANCC polyclonal antibody and antigen (Figure B) at 4? overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm and nucleus.
Immunohistochemistry-Paraffin: FANCC Antibody [NBP3-12777]

Immunohistochemistry-Paraffin: FANCC Antibody [NBP3-12777]

Immunohistochemistry-Paraffin: FANCC Antibody [NBP3-12777] - Staining of human FANCC in human brain with rabbit polyclonal antibody (1:2000).
Immunohistochemistry-Paraffin: FANCC Antibody [NBP3-12777]

Immunohistochemistry-Paraffin: FANCC Antibody [NBP3-12777]

Immunohistochemistry-Paraffin: FANCC Antibody [NBP3-12777] - Staining of human FANCC in human pancreas with rabbit polyclonal antibody (1:2000).

Applications for FANCC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:300-1:10000

Immunohistochemistry-Paraffin

1:1000-1:4000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FANCC

The Fanconi anemia group C protein (FANCC) is a member of the Fanconi anemia complementation. FANCC functions as a cell cycle checkpoint to delay the onset of apoptosis and promotes homologous recombination repair of damaged DNA. FANCC may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in FANCC portein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in many congenital malformations and predisposition to malignant formations.

FANCC antibodies are useful for DNA repair studies and cell cycle research.

Long Name

Fanconi Anemia Complementation Group C

Alternate Names

FA Complementation Group C, FA3, FACC

Gene Symbol

FANCC

Additional FANCC Products

Product Documents for FANCC Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FANCC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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