FANCF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00002188-B01P

Novus Biologicals, part of Bio-Techne
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H00002188-B01P
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FANCF Antibodies »

Product Specifications

Immunogen

FANCF (NP_073562.1, 1 a.a. - 374 a.a.) full-length human protein. MESLLQHLDRFSELLAVSSTTYVSTWDPATVRRALQWARYLRHIHRRFGRHGPIRTALERRLHNQWRQEGGFGRGPVPGLANFQALGHCDVLLSLRLLENRALGDAARYHLVQQLFPGPGVRDADEETLQESLARLARRRSAVHMLRFNGYRENPNLQEDSLMKTQAELLLERLQEVGKAEAERPARFLSSLWERLPQNNFLKVIAVALLQPPLSRRPQEELEPGIHKSPGEGSQVLVHWLLGNSEVFAAFCRALPAGLLTLVTSRHPALSPVYLGLLTDWGQRLHYDLQKGIWVGTESQDVPWEELHNRFQSLCQAPPPLKDKVLTALETCKAQDGDFEVPGLSIWTDLLLALRSGAFRKRQVLGLSAGLSSV

Specificity

This product is specific for Human FANCF purified MaxPab mouse polyclonal antibody (B01P) [Gene ID: 2188].

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for FANCF Antibody

Western Blot: FANCF Antibody [H00002188-B01P]

Western Blot: FANCF Antibody [H00002188-B01P]

Western Blot: FANCF Antibody [H00002188-B01P] - Analysis of FANCF expression in transfected 293T cell line by FANCF polyclonal antibody. Lane 1: FANCF transfected lysate(41.14 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: FANCF Antibody [H00002188-B01P]

Immunocytochemistry/ Immunofluorescence: FANCF Antibody [H00002188-B01P]

Immunocytochemistry/Immunofluorescence: FANCF Antibody [H00002188-B01P] - Analysis of purified antibody to FANCF on HeLa cell. (antibody concentration 10 ug/ml)

Applications for FANCF Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FANCF

FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. Defects in FANCF are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level, it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.

Alternate Names

FAF, Fanconi anemia group F protein, Fanconi anemia, complementation group F, MGC126856, Protein FACF

Gene Symbol

FANCF

UniProt

NP_073562.1 (Human)

Additional FANCF Products

Product Documents for FANCF Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FANCF Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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